A novel plasmid carrying blaCTX-M-15 identified in commensal Escherichia coli from healthy pregnant women in Ibadan, Nigeria

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dc.contributor.authorFortini D
dc.contributor.authorFashae K
dc.contributor.authorVilla L
dc.contributor.authorFeudi C
dc.contributor.authorGarcía-Fernández A
dc.contributor.authorCarattoli A
dc.date.accessioned2022-07-23T09:28:16Z
dc.date.available2022-07-23T09:28:16Z
dc.date.issued2015
dc.descriptionJournal of Global Antimicrobial Resistance
dc.description.abstractThe aim of this study was to investigate the molecular characteristics of commensal Escherichia coli producing extended-spectrum β-lactamases and showing fluoroquinolone resistance circulating in a healthy population in Ibadan, Nigeria. In total, 101 faecal samples from healthy pregnant women on the day of admission to hospital were collected and plated on eosin–methylene blue agar supplemented with cefotaxime. Genotyping demonstrated the presence of the blaCTX-M-15 gene in all of the cefotaxime-resistant isolates (n=32), and there was circulation of prevalent clones. The aac(6′)-Ib-cr, qnrS1, qepA1 and qnrB1 genes were identified in several strains. A novel plasmid supporting the spread of the blaCTX-M-15, blaTEM-1 and qnrS1 genes was identified in these isolates by complete DNA sequencing.
dc.identifier.citation10.1016/j.jgar.2014.12.002
dc.identifier.issn2213-7165
dc.identifier.urihttps://databank.ned.gov.ng/handle/123456789/98
dc.language.isoen
dc.subjectPlasmid-mediated quinolone resistance
dc.subjectPMQR
dc.subjectIncF plasmid
dc.titleA novel plasmid carrying blaCTX-M-15 identified in commensal Escherichia coli from healthy pregnant women in Ibadan, Nigeria
dc.typeArticle
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